Process for the synthesis of ivabradine and addition salts...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C540S523000

Reexamination Certificate

active

07867994

ABSTRACT:
Process for the synthesis of ivabradine of formula (I):addition salts thereof with a pharmaceutically acceptable acid and hydrates thereof.α crystalline form of ivabradine hydrochloride.Medicinal products containing α crystalline form of ivabradine hydrochloride, which are useful as bradycardics.

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Eurasian Search Reportfor Eurasian Application No. 200500238, Jun. 6, 2005.
International Search Reportfor International Application No. PCT/FR2005/000394, Jun. 30, 2005.
Sorbera, et al.,Drugs of the Future, 2003, 28, 652-658.

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