Process for the synthesis of functionalized indolizidines

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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Reexamination Certificate

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11407752

ABSTRACT:
The present invention provides a process for the preparation of functionalized indolizidines comprising the steps and products disclosed within this application.

REFERENCES:
patent: 5028614 (1991-07-01), Liu et al.
Park et al, 2001, Tetrahedron: Asymmetry, vol. 12, p. 2621-2624.
Ring Closing Metathesis (RCM), retrieved from Internet on Mar. 16, 2007, <http://www.organic-chemistry.org
amedreactions/ring-closing-metathesis.shtm>.
Patil et al., “A Short and Efficient Synthesis of 1-deoxy-castanospermine and 1-deoxy-8a-epi-castanospermine”, Tetrahedron Letters, vol. 42 (2001) pp. 747-749.
Koskinen et al., “Polyhydroxylated Indolizidine Alkaloids-an Efficient Synthesis of 1-deoxy-8,8a-di-epi-castanospermine”, Tetrahedron, vol. 59 (2003) pp. 6947-6954.

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