Process for the synthesis of 3-chloro-2,4,5-trifluorobenzoic aci

Details Process for the synthesis of 3-chloro-2,4,5-trifluorobenzoic aci Process for the synthesis of 3-chloro-2,4,5-trifluorobenzoic aci

1988-10-28

1989-12-05

Reamer, James H.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acids and salts thereof

562456, 560 47, C07C 51363

Patent

active

048853860

ABSTRACT:
An improved process for the preparation of 3-chloro-2,4,5-trifluorobenzoic acid is described which involves reaction of a diester of 3,4,5,6-tetrafluoro-1,2-benzenedicarboxylic acid with a substituted amine to afford 3-amino-2,4,5-trifluorobenzoic acid followed by subsequent conversion of the amio intermediate into 3-chloro-2,4,5-trifluorobenzoic acid.

REFERENCES:
patent: 4359428 (1982-11-01), Jacobs et al.
patent: 4439620 (1984-03-01), Klauke et al.
patent: 4771054 (1988-09-01), Domagala et al.
patent: 4782179 (1988-11-01), Hirota et al.

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