Process for the synthesis of...

Organic compounds -- part of the class 532-570 series – Organic compounds – Nitriles

Reexamination Certificate

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C558S414000

Reexamination Certificate

active

10030665

ABSTRACT:
A new process is disclosed for the synthesis of racemic or optically pure N-[4-cyano-3-trifluoro-methyl-phenyl]-3[4-fluorophenyl-sulfonyl]-2-hydroxy-2-methylpropionamide. The process includes the formation of several novel intermediates in the synthesis.

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patent: WO 98/55153 (1998-12-01), None
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J. Med. Chem. 1988, 31, 885-887; Howard Tucker et al; Resolution of the Nonsteroidal Antiandrogen 4′-Cyano . . . .
Epoxidation of Olefins; Jan. 5, 1955; vol. 77; pp. 89-92; William D. Emmons et al; Peroxytrifluoroacetic Acid. IV.
Vol. 81; pp. 680-683; Feb. 5, 1959; Donald L. MacPeek et al; Synthesis of Glycidic Esters by Epoxidation of . . . .
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Zh. Org. Khim.; vol. 7; B.T. Hockoe; 1971; pp. 2221-2222.

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