Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1997-07-09
1999-01-19
Marschel, Ardin H.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
536 231, 536 253, C07H 1900, C07H 2100, C07H 2102
Patent
active
058614931
ABSTRACT:
Improved processes for the synthesis of 2'-O-substituted pyrimidine nucleosides are provided. The processes feature alkylation of a 2,2'-anhydropyrimidine nucleoside or a 2S,2'-anhydropyrimidine nucleoside with a weak nucleophile in the presence of a Lewis acid.
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Cook Phillip Dan
Ross Bruce S.
Sprankle Kelly G.
Springer Robert H.
ISIS Pharmaceuticals Inc.
Marschel Ardin H.
Riley Jezia
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