Process for the synthesis natural aromatics

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing nitrogen-containing organic compound

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435135, 435198, 435921, C12P 1300, C12P 762

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active

054379911

ABSTRACT:
A novel method for the production of natural aromatic ester compounds such as methyl anthranilate, ethyl anthranilate butyl anthranilate methyl cinnamate and methyl salicylate comprises the esterification of their corresponding acids using microbially derived enzymes in the presence of a C.sub.1 -C.sub.4 alcohol such as methanol, ethanol or butanol. A biphasic reaction medium may optionally be utilized to generate maximum yields through the addition of a non-polar organic solvent such as hexane, ethyl acetate, heptane and the like.

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Miller et al "JAOCS" vol. 65 No. (Jun. 1985) pp. 927-931.
Chen et al "J. Am. Chem. Soc." vol. 109 No. 9 (1987) pp. 2812-2817.
Lazar et al "World Conference of Emerging Tech" Fats, Oils, Ind (1985) pp. 346-354.
Derwent ABS (J52070057) Jun. 1977 Ohoshi Syoyu.
Derwent ABS J51061673 (May 1976) Snow Brand Milk.

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