Process for the synthesis and crystalline form of agomelatine

Organic compounds -- part of the class 532-570 series – Organic compounds – Amino nitrogen containing

Reexamination Certificate

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C514S617000

Reexamination Certificate

active

11052630

ABSTRACT:
A process for the industrial synthesis and a new crystalline form of the compound of formula (I):Medicinal products containing the same which are useful in treating disorders of the melatoninergic system.

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patent: 2005/0164987 (2005-07-01), Barberich
patent: 0447285 (1991-09-01), None
French Search Report for French Application No. 04.01439, Sep. 15, 2004.
European Search Report for European Application No. 05290308, May 20, 2005.
International Search Report for International Application No. PCT/FR2005/000327, Jun. 16, 2005.
Depreux, et al.,J. Med. Chem.,1994, 37, 3231-3239.
Tinant, et al.,Acta Cryst,, 1994, C50, 907-910.

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