Process for the synthesis and crystalline form agomelatine

Details Process for the synthesis and crystalline form agomelatine Process for the synthesis and crystalline form agomelatine

2007-04-06

2009-06-09

Kumar, Shailendra (Department: 1621)

Organic compounds -- part of the class 532-570 series

Organic compounds

Amino nitrogen containing

C564S130000, C514S617000, C558S351000

Reexamination Certificate

active

07544839

ABSTRACT:
Process for the industrial synthesis and new crystalline form of the compound of formula (I):Medicinal products containing the same which are useful in treating disorders of the melatoninergic system.

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Depreux et al, J. Med. Chem., 1994, 37, 3231-3239.
French Search Report for French Application No. 04.01439, Sep. 15, 2004.
European Search Report for European Application No. 05290308, May 20, 2005.
International Search Report for International Application No. PCT/FR2005/000327, Jun. 16, 2005.
Depreux, et al.,J. Med. Chem., 1994, 37, 3231-3239.
Tinant, et al.,Acta. Cryst., 1994, C50, 907-910.

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