Process for the synchronization of ovulation

Details Process for the synchronization of ovulation Process for the synchronization of ovulation

1995-07-03

1996-12-31

Spivack, Phyllis G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 15, 514573, A61K 3824, A61K 3119

Patent

active

055894577

ABSTRACT:
A method for synchronizing ovulation in cattle by sequential injection of hormones is disclosed. A hormone selected from the group consisting of gonadotropin releasing hormone (GnRH), luteinizing hormone (LH), or human chorionic gonadotropin (hCG) is administered to an open cow during an estrous cycle in order to stimulate follicle development. Prostaglandin F.sub.2.alpha. (PGF.sub.2.alpha.) is then administered to initiate corpus luteum regression about five to eight days after administration of the GnRH, LH or hCG. A second dose of GnRH, LH or hCG is then administered concomitantly with the PGF.sub.2.alpha. injection or up to about three days after the PGF.sub.2.alpha. injection. This second dose of hormone functions to stimulate the ovulation of a dominant follicle and the cow is then breed within one day of the administration of the second dose of hormone.

REFERENCES:
patent: 4780451 (1988-10-01), Donaldson
patent: 4845077 (1989-07-01), Hodgen
patent: 5180711 (1993-01-01), Hodgen
patent: 5288705 (1994-02-01), Zohar
patent: 5378688 (1995-01-01), Nett
Pursley et al., J. Anim. Sci. (72) Suppl. 1/J. Dairy Sci. (77) Suppl. 1/1994, 69.

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