Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acid esters
Patent
1990-12-21
1993-02-23
Dees, Jose G.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carboxylic acid esters
549 34, 560151, 562581, 562582, 564160, C07C 69675, C07C 6970
Patent
active
051892006
ABSTRACT:
An efficient and commerically-viable method for the stereoselective transformation of a diol to an alcohol is disclosed. The present method is particularly well-suited for the preparation of the unnatural D-isomer of malic acid or its derivatives from the abundant naturally occurring L-tartaric acid or derivatives thereof.
REFERENCES:
patent: 4960904 (1990-10-01), LeRoy et al.
patent: 5023342 (1991-06-01), Sharpless et al.
Pizey, Synthetic Reagents, vol. 1, pp. 331-333, (J. Wiley, 1974).
Chibata et al., Pure Appl. Chem. 50: 667 (1978).
Wynberg et al., J. Am. Chem. Soc. 104: 166 (1982).
Henrot et al., Synth. Commun. 16: 183 (1986).
Hungerbuhler et al., Angew. Chem. Int. Ed. Engl. 18: 958 (1979).
Alpegiani et al., J. Org. Chem. 52: 278 (1987).
Gao et al., J. Am. Chem. Soc. 110: 7538 (1988).
Kusuda et al., Tetrahedron Lett. 30: 2945 (1989).
Beilsteins HandBuch der Organischen Chemie, Band III, 417-420.
Schiller, E., Berichte 42: 2017 (1909).
Stinson, S., Chemical & Engineering News, p. 22, Oct. 31, 1988.
Dees Jos,e G.
Frazier B.
Sepracor Inc.
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