Process for the stereoselective synthesis of 16-substituted-4-az

Details Process for the stereoselective synthesis of 16-substituted-4-az Process for the stereoselective synthesis of 16-substituted-4-az

1999-05-11

2000-11-07

Rotman, Alan L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Four or more ring nitrogens in the bicyclo ring system

544238, 544316, 544408, 546 78, C07D40112, C07D40312, C07D22118, C07D24108, C07D25306

Patent

active

061438871

ABSTRACT:
The novel process of the present invention involves the stereoselective synthesis of certain 16.beta.-substituted 4-aza-5.alpha.-androstan-3-ones and the useful intermediates obtained therein.

REFERENCES:
patent: 5455348 (1995-10-01), Austel et al.
patent: 5719158 (1998-02-01), Durette et al.
patent: 5739137 (1998-04-01), Durette et al.
patent: 5910497 (1999-06-01), Durette et al.
Zhao et al., Tet. Letters, vol. 38, No. 31 (1997), pp. 5437-5440, "Syntheses of alkylated malonates in a traceless linker derived soluble polymer support".

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