Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing oxygen-containing organic compound
Reexamination Certificate
2006-04-04
2006-04-04
Lilling, Herbert J. (Department: 1651)
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing oxygen-containing organic compound
C435S145000, C435S195000, C435S196000, C435S254200
Reexamination Certificate
active
07022503
ABSTRACT:
The present invention relates to a process for the kinetic resolution of racemic functionalized epoxides in the presence of microorganisms, crude or pure preparations thereof comprising a polypeptide having epoxide hydrolase activity. Preferred microorganisms are yeasts and bacteria which may also be recombinant.
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Weijers, Carel A. G. M. et al;“Epoxide hydrolases from yeasts and other sources: versatile tools in biocatalysis” retrieved from STN Database accession No. 130:293060, XP002189633 *abstract* & J. Mol. Catal. B: Enzym. (1999), 6(3), 199-214.
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Visser , H. et al: “Cloning and characterization of an epoxide hydrolase-encoding gene fromRhodotorula glutinis”retrieved from STN, Database accession No. 133:234299, XP002189630 *abstract* & Appl. Microbiol. Biotechnol. (2000), 53(4), 415-419.
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Botes, A. L. et al: “Biocatalytic resolution of 1,2-epoxyoctane using resting cells of different yeast strains with novel epoxide hydrolase activities” retrieved from STN Database accession No. 129:25538, XP002189632 *abstract* & Biotachnol. Lett. (1998), 20(4), 421-426.
De Bont Jan A. M.
De Oliveira Villela Filho Murillo
Dreisbach Claus
Liese Andreas
Verdoes Jan C.
Bayer Aktiengesellschaft
Forschungszentrum Juelich GmbH
Lilling Herbert J.
Seng Jennifer R.
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