Process for the stabilization of vesicles of amphiphilic lipid(s

Details Process for the stabilization of vesicles of amphiphilic lipid(s Process for the stabilization of vesicles of amphiphilic lipid(s

1994-02-14

2000-04-18

Kishore, Gollamudi S

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Liposomes

264 41, 264 43, 4284022, 514844, A61K 9127, A61K 700

Patent

active

060512504

ABSTRACT:
The invention relates to a process for stabilization of vesicles formed from a lipid-phase membrane containing at least one ionic and/or nonionic amphiphilic lipid encapsulating an aqueous phase, in the form of a dispersion in an aqueous phase, by addition of at least one stabilizing agent to the aqueous dispersion phase, in which the stabilizing agent (s) is/are chosen from the group composed of glycerol alginates, propylene glycol alginates, gellan gum and wellan gum. The invention also relates to a composition for topical application containing vesicles stabilized by the said process.

REFERENCES:
patent: 4670185 (1987-06-01), Fujiwara
patent: 4708861 (1987-11-01), Popescu
patent: 4830857 (1989-05-01), Handjani
patent: 5008109 (1991-04-01), Tin
patent: 5290562 (1994-03-01), Meybeck
patent: 5332595 (1994-07-01), Gaonkar
Kaoru, "Preparation of Heat-Resistant Emulsified Fat and Oil", Patent Abstracts of Japan, vol. 13, No. 208 (C-596) 1989 & JP-A-10 27 634.

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