Process for the splitting of the racemate of d-1-phenylpropanola

Details Process for the splitting of the racemate of d-1-phenylpropanola Process for the splitting of the racemate of d-1-phenylpropanola

1974-10-10

1976-05-25

Gallagher, Richard J.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2605706, C07D27706

Patent

active

039593029

ABSTRACT:
The d,1-phenylpropanolamine(norephedrine) racemate is split with optically active thiazolidine-4-carboxylic acids of the formula: ##EQU1## where R.sub.1 and R.sub.2 are both methyl or are joined together to form the pentamethylene group.

REFERENCES:
patent: 1867274 (1932-07-01), Manske
patent: 2450784 (1948-10-01), Duffin et al.
Stewart, Stereochemistry, Lengmans, Green and Co., London, 1919, pp. 40-42.

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