Process for the single crystallization of enatiomeric ratio's (2

Organic compounds -- part of the class 532-570 series – Organic compounds – Unsubstituted hydrocarbyl chain between the ring and the -c-...

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540488, C07D28102

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active

053150058

ABSTRACT:
A purification method of intermediates for the preparation of Diltiazem which consists of the crystallization of a mixture enantiomerically enriched in (2S,3S)-2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H) -one is described.

REFERENCES:
patent: 3562257 (1971-02-01), Kugita et al.
patent: 4416819 (1983-11-01), Nagao et al.
patent: 4420628 (1983-12-01), Inoue et al.
patent: 4533748 (1985-08-01), Manghisi et al.
March, J. Advance Organic Chemistry, John Wiley and Sons, New York, 1985, pp. 104-107.
Hiroatsu et al; Chemical Abstract vol 90, 1979, 90: 6431w.
Biserka et al; Chemical Abstract vol. 101, 1984, 101: 109919m.
Merck Index, X Ed., No. 3189, p. 466, 1983.
The Pharmacopoeia of Japan, English Version, XI Edition (1986).
Chem. Abstract. 75:36164u (JP 71/8982-Tanabe Seiyaku Co., Ltd.), 1975.
Helvetica Chimica Acta, vol. 67, No. 3, 2 May 1984, pp. 916-926.
Organicum, pp. 38-39, 1973.
Encyclopedia of Chemical Technology, 3rd Edition, vol. 7, pp. 247, 260, 261, 1978.
Merck Index, X Ed., No. 3189, p. 466, 1983.

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