Process for the simultaneous production of benanomicins A and B

Details Process for the simultaneous production of benanomicins A and B Process for the simultaneous production of benanomicins A and B

1991-06-14

1994-01-11

Griffin, Ronald W.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing compound containing saccharide radical

435105, 536 64, 536 181, C12P 1912

Patent

active

052780520

ABSTRACT:
Benanomicin A and Benanomicin B are fermentatively produced by the cultivation of a new microorganism Actinomadura spadix, designated as MH193-16F4 strain.

REFERENCES:
patent: 4870165 (1989-09-01), Oki et al.
The Journal of Antibiotics, vol. 40, Aug. 1987, pp. 1104-1110.
Matsuda, Y. et al.; "KS-619-1, a new inhibitor of Ca.sup.2+ and calmodulin dependent cyclic nucleotide phosphodiesterase from Streptomyces Californicus".
Can. J. Chem., vol. 62, 1984, pp. 2818-2821; N. N. Gerber et al.; "Novel benzo [a] naphthacene quinones from actinomycete, Frankia G-2 (ORS 020604)".
The Journal of Antibiotics, vol. 41, No. 6, Jun. 1988, pp. 807-811; T. Takeuchi et al.; "New antifungal antibiotics, benomicins A and B from an Actinomycete".

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