Process for the simultaneous obtention of insulin and pancreatin

Details Process for the simultaneous obtention of insulin and pancreatin Process for the simultaneous obtention of insulin and pancreatin

1975-12-18

1977-06-14

Phillips, Delbert R.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2601125R, C07C10352

Patent

active

040296415

ABSTRACT:
A process for the simultaneous obtention of insulin and pancreatin from fresh or deep frozen swine pancreases by extracting the glands at a pH of about 5 to 7 with a reaction mixture containing at least 40% of acetone, separating the extracted substance and the remaining solids, instantly adjusting the solids to a pH of above 5.6 with a buffer, and then recovering insulin from the extraction mixture and pancreatin from the solids.

REFERENCES:
patent: 2573099 (1951-10-01), Frederiksen
patent: 2752286 (1956-06-01), Schultz et al.
patent: 2779706 (1957-01-01), Homan
patent: 2897117 (1959-07-01), Romans
patent: 3720657 (1973-03-01), DEVries
VanTruyen et al.: Chem. Abstr. 75:101214b (1971).

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