Process for the separation and recovery of nosiheptide

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Using a micro-organism to make a protein or polypeptide

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435119, C12P 2104, C12P 1718

Patent

active

050932438

ABSTRACT:
Nosiheptide is recovered from a cultivation mixture obtained by cultivating a Nosiheptide-producing strain of Streptomyces by adding a water-miscible organic solvent, removing mycelia, precipitating Nosiheptide by adding water, which may be acidified, and recovering the Nosiheptide.

REFERENCES:
patent: 3155581 (1964-11-01), Pinnert et al.
patent: 4384043 (1983-05-01), Martin et al.
patent: 4584134 (1986-04-01), Morioka et al.

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