Process for the selective sulfoxide reduction of 3-hydroxy cephe

Details Process for the selective sulfoxide reduction of 3-hydroxy cephe Process for the selective sulfoxide reduction of 3-hydroxy cephe

1995-12-22

1997-09-02

Ford, John M.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D49904

Patent

active

056633300

ABSTRACT:
Process for selectively reducing cephalosporin sulfoxides of 3-hydroxy cephem and 3-methylene cepham compounds by treatment with a chlorinating agent in the presence of a solvent and a base, which are both inert to the chlorinating agent.

REFERENCES:
patent: 4137407 (1979-01-01), Murakami et al.
patent: 4695627 (1987-09-01), Verweij et al.
Chemical Abstracts, vol. 85, No. 15, AN 108653j, Oct. 11, 1976, JP-A-76 034 188, Mar. 23, 1976.

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