Process for the selective increase of production of antibiotic G

Details Process for the selective increase of production of antibiotic G Process for the selective increase of production of antibiotic G

1997-09-30

1999-03-16

Lankford, Jr., Leon B.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Using a micro-organism to make a protein or polypeptide

435 711, 435 712, 435822, 514 9, C12P 2104, A61K 3800

Patent

active

058829008

ABSTRACT:
A method for increasing both total antibiotic yield the selective production of factor A of the GE 2270 antibiotics consisting in the addition of vitamin B.sub.12 or its analogs having vitamin B.sub.12 --like activity to the fermentation media of Planobispora rosea ATCC 53773 or any antibiotic GE 2270 producing mutant or variant thereof.

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Selva et al. J. Antibiot. vol. 44, pp. 693-701 (1991).

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