Process for the selective extracorporeal precipitation of low-de

Details Process for the selective extracorporeal precipitation of low-de Process for the selective extracorporeal precipitation of low-de

1987-11-20

1990-03-13

Schain, Howard E.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

436 86, 436 87, 514 54, 514 55, 514 56, 514 61, 530359, C07K 1516, A61K 3702

Patent

active

049083546

ABSTRACT:
A method of precipitating low-density lipoproteins which comprises administering to a volume of blood, plasma or solutions containing blood or plasma a therapeutically or diagnostically effective amount of a low-density lipoprotein precipitating substance at an acid pH such that an anticoagulent effect associated with heparin is minimized or eliminated. The substances utilized in such a method include hydrolyzed heparin, hydrolyzed heparin acylated at free amine groups, sulfated glycosamino glycan and sulfated polysaccharides.

REFERENCES:
patent: 3920625 (1975-11-01), Andersson et al.
patent: 4045176 (1977-08-01), Proksch et al.
patent: 4096136 (1978-06-01), Ayers et al.
patent: 4103685 (1978-08-01), Jupien et al.
patent: 4110077 (1978-08-01), Klein et al.
patent: 4287180 (1981-09-01), Thomas
patent: 4309188 (1982-01-01), Bentzen
patent: 4473553 (1984-09-01), Zuffi et al.

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