Process for the ring cleavage of 2-isopropyl-5,5-dimethylthiazol

Details Process for the ring cleavage of 2-isopropyl-5,5-dimethylthiazol Process for the ring cleavage of 2-isopropyl-5,5-dimethylthiazol

1987-02-24

1988-03-15

Shippen, Michael L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acids and salts thereof

C07C149243

Patent

active

047314770

ABSTRACT:
A process for the ring cleavage of 2-isopropyl-5,5-dimethylthiazolidines in aqueous acid medium at elevated temperature. Whenever the five ring in the 4-position is substituted by a carboxyl group, penicillamine is the resultant product.

REFERENCES:
patent: 2477148 (1949-07-01), Sheehan
patent: 3888923 (1975-06-01), Asinger
patent: 3946069 (1976-03-01), Asinger
patent: 3948984 (1976-04-01), Asinger
patent: 4028406 (1977-06-01), Asinger
patent: 4045479 (1977-08-01), Asinger
patent: 4060548 (1977-11-01), Asinger

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