Process for the resolution of d,1 2-(6-methoxy-2-naphthyl)propio

Details Process for the resolution of d,1 2-(6-methoxy-2-naphthyl)propio Process for the resolution of d,1 2-(6-methoxy-2-naphthyl)propio

1980-06-04

1985-05-07

Reamer, James H.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Radical -xh acid, or anhydride, acid halide or salt thereof...

26050117, C07C 9100, A61K 3119

Patent

active

045158118

ABSTRACT:
Mixtures of d 2-(6-methoxy-2-naphthyl)propionic acid and 1 2-(6-methoxy-2-naphthyl)propionic acid or soluble salts thereof are resolved with N-R-D-glucamine or salts thereof, where R is alkyl having 2 to 36 carbon atoms or cycloalkyl having 3 to 8 carbon atoms, to yield a product substantially enriched in d 2-(6-methoxy-2-naphthyl)propionic acid.

REFERENCES:
patent: 3904682 (1975-09-01), Fried et al.
Henzl et al., Chem. Absts., 83, 84872(k), 1975.
Sekhar, Chem. Absts., 85, 37229(n), 1976.
Nadell et al., Chem. Absts., 81, 45510(e), 1974.

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