Process for the resolution of d,1 2-(6-methoxy-2-naphthyl)propio

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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562466, 562401, 424316, 564507, C07C 9110, A61K 31205, C07B 1900, C07C 6524

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042461936

ABSTRACT:
Mixtures of d 2-(6-methoxy-2-naphthyl)propionic acid and 1 2-(6-methoxy-2-naphthyl)propionic acid or soluble salts thereof are resolved with N-R-D-glucamine or salts thereof, where R is alkyl having 2 to 36 carbon atoms or cycloalkyl having 3 to 8 carbon atoms, to yield a product substantially enriched in d 2-(6-methoxy-2-naphthyl)-propionic acid.

REFERENCES:
patent: 2016962 (1935-10-01), Flint et al.
patent: 2016963 (1935-10-01), Flint et al.
patent: 3904682 (1975-09-01), Fried et al.
patent: 3904683 (1975-09-01), Day et al.
patent: 3906038 (1975-09-01), Fried et al.
Greenstein et al., Chem. of the Amimo Acids, John Wiley & Sons, Inc., N.Y., vol. 1, pp. 715-728, (1961).

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