Process for the removal of the formyl group from N-formyl peptid

Details Process for the removal of the formyl group from N-formyl peptid Process for the removal of the formyl group from N-formyl peptid

1982-04-26

1984-02-28

Phillips, Delbert R.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

C07C10352

Patent

active

044340974

ABSTRACT:
A process for the removal of the formyl group in N-formylated peptides or their esters is described. The N-formyl compound is reacted with hydrazine or a substituted hydrazine of formula I: ##STR1## at a pH between 1 and 3.5, keeping the pH constant during the reaction. The process is particularly useful for the preparation of aspartam.

REFERENCES:
Chemical Abstracts, vol. 55, 1961, Abstract No. 18612b, (I).
Chemical Abstracts, vol. 70, 1969, Abst. No. 4596s, (II).
Chemical Abstracts, vol. 69, 1968, Abst. No. 67692v, (III).
Lefrancier et al., Memories Presentes a la Societe Chimique, Feb. 4, 1965, pp. 3668-3675.

Affiliated with

Also associated with

Rating

Process for the removal of the formyl group from N-formyl peptid does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for the removal of the formyl group from N-formyl peptid, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for the removal of the formyl group from N-formyl peptid will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-758625