Process for the recovery of a water-insoluble epoxy alcohol

Distillation: processes – separatory – With disparate physical separation – Utilizing removing solid from liquid

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159DIG16, 159DIG23, 203 67, 203 69, 203 70, 203 77, 203 80, 549529, 549541, 549542, 549554, B01D 310, C07D30132

Patent

active

049351010

ABSTRACT:
Water-insoluble crystallizable epoxy alcohols such as phenyl glycidol are recovered from epoxidation reaction mixtures by washing the mixture with water, concentrating the mixture by distillation under vacuum to remove unreacted hydroperoxide and alcohol co-product, and crystallizing the epoxy alcohol from solution. Minimal decomposition of the epoxy alcohol is observed.

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Sharpless [J. Am. Chem. Soc., 109, 5765, (1987)].

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