Process for the purification of recombinant human beta interfero

Drug – bio-affecting and body treating compositions – Lymphokine – Interferon

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Details

530351, 530416, 435 6951, C12P 2100, C12N 1522, C07K 1526

Patent

active

052446557

ABSTRACT:
A process is described for the purification of recombinant human beta interferon which comprises the use of three chromatographic stages carried out in series, utilizing as stationary phases: glass particles of controlled porosity, cation exchange polymer resins and polymer resins able to complex heavy metals.

REFERENCES:
patent: 4765903 (1988-08-01), D'Andrea et al.
patent: 4808523 (1989-02-01), Revel et al.
patent: 5004605 (1991-04-01), Hershenson et al.
patent: 5037644 (1991-08-01), Shaked et al.

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