Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2005-06-09
2010-06-01
Chu, Yong (Department: 1626)
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
active
07728151
ABSTRACT:
A dicyclohexyamine salt of compound of formula I, namely perindopril, having an X-ray powder diffraction pattern with characteristic peaks (2θ): 8.462, 10.624, 18.693, 9.424, 17.272, 14.177, 19.499, 20.765, 21.409, and 14.540.A process for preparation of the said salt of perindopril and its use in the purification of an impure perindopril and a process for purification of perindropril comprising formation of its salt with dicyclohexylamine. The present invention also relates to preparation of Perindopril tert-butyl amine salt directly from Perindopril dicyclohexylamine salt without isolating the free base.
REFERENCES:
patent: 7445296 (2008-11-01), Chen
patent: WO 2004/075889 (2004-09-01), None
PCT International Search Report for PCT/IN2005/000189, mailed Mar. 3, 2006.
Dhake Vilas Nathu
Godbole Himanshu Madhav
Nehate Sagar Purushottam
Rananaware Umesh Babanrao
Singh Girij Pal
Chu Yong
Lupin Limited
Merchant & Gould P.C.
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