Process for the purification of opacifying contrast agents

Details Process for the purification of opacifying contrast agents Process for the purification of opacifying contrast agents

1997-02-20

1998-09-22

Raymond, Richard L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Amino nitrogen containing

210635, 210639, 424 935, 424 937, 424 943, 424 9425, 424 9454, 424 95, 536 55, A61K 4904, C07C23364

Patent

active

058115811

ABSTRACT:
A process for the purification of opacifying contrastographic agents, comprising chromatographic and nanofiltration techniques combined together, the subsequent chromatographic separation of the crude product solution and a nanofiltration step, with a final deionization on ion exchange resins.

REFERENCES:
patent: 5160437 (1992-11-01), Bosworth et al.
patent: 5204005 (1993-04-01), Doran et al.
patent: 5210300 (1993-05-01), Kneller
patent: 5447635 (1995-09-01), Viscardi et al.

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