Process for the purification of meloxicam

Details Process for the purification of meloxicam Process for the purification of meloxicam

2011-08-30

2011-08-30

Oh, Taylor Victor (Department: 1622)

Organic compounds -- part of the class 532-570 series

Organic compounds

Chalcogen in the nitrogen containing substituent

Reexamination Certificate

active

08008480

ABSTRACT:
A process for purifying meloxicam form I from a crude meloxicam, which comprises:i. contacting the crude meloxicam with an amine in a non-aqueous solvent to form a meloxicam salt;ii. isolating the meloxicam salt;iii. dissolving the meloxicam salt in an aqueous solvent to form a salt solution; andiv. adding an acid to the salt solution to precipitate free meloxicam.

REFERENCES:
patent: 4233299 (1980-11-01), Trummlitz et al.
patent: 2003/0109701 (2003-06-01), Coppi et al.

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