Process for the purification of IL-18 binding protein

Details Process for the purification of IL-18 binding protein Process for the purification of IL-18 binding protein

2005-06-27

2008-10-21

Mertz, Prema (Department: 1646)

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

Separation or purification

C530S420000, C530S421000

Reexamination Certificate

active

07439336

ABSTRACT:
The invention relates to a process for the purification of IL-18 binding protein (IL-18BP) from a fluid using aqueous two-phase partitioning.

REFERENCES:
patent: 4508825 (1985-04-01), Kim et al.
patent: 4579661 (1986-04-01), Gustafsson et al.
patent: 4591563 (1986-05-01), Paul et al.
patent: 4684723 (1987-08-01), Dove et al.
patent: 4728613 (1988-03-01), Brewer et al.
patent: 4743550 (1988-05-01), Ananthapadmanabhan et al.
patent: 5093254 (1992-03-01), Giuliano et al.
patent: 5139943 (1992-08-01), Heinsohn et al.
patent: 5328841 (1994-07-01), Lorch et al.
patent: 5407579 (1995-04-01), Lee et al.
patent: 5407810 (1995-04-01), Builder et al.
patent: 5907035 (1999-05-01), Guinn
patent: 6437101 (2002-08-01), Hayenga et al.
patent: 6454950 (2002-09-01), Tjerneld et al.
patent: 6559284 (2003-05-01), Ageland et al.
patent: 2007/0037734 (2007-02-01), Rossi et al.
patent: 2007/0134761 (2007-06-01), Chatellard et al.
patent: 2007/0196895 (2007-08-01), Aloni et al.
patent: 2007/0258962 (2007-11-01), Chatellard et al.
patent: 2008/0076708 (2008-03-01), Altarocca et al.
patent: 0477284 (1995-08-01), None
patent: 1 110 969 (2001-06-01), None
patent: WO 92/07868 (1992-05-01), None
patent: WO 96/23061 (1996-08-01), None
patent: WO 99/09063 (1999-02-01), None
patent: WO 00/68260 (2000-11-01), None
patent: WO 2004/101617 (2004-11-01), None
patent: WO 2005/040384 (2005-05-01), None
patent: WO 2005/049649 (2005-06-01), None
patent: WO 2005/083058 (2005-09-01), None
patent: WO 2006/128908 (2006-12-01), None
patent: WO 2006/131550 (2006-12-01), None
Altschul, S. F. et al. “Basic Local Alignment Search Tool”,J. Mol. Biol., 1990, pp. 403-410, vol. 215.
Altschul, S. F. et al. “Gapped BLAST and PSI-BLAST: a new generation of protein database search programs”,Nucleic Acids Research, 1997, pp. 3389-3402, vol. 25, No. 17.
Balasubramaniam, D. et al. “Tobacco protein separation by aqueous two-phase extraction”,Journal of Chromatography A, 2003, pp. 119-129, vol. 989.
Baskir, J. N. et al. “Thermodynamics of the Separation of Biomaterials in Two-Phase Aqueous Polymer Systems: Effect of the Phase-Forming Polymers”,Macromolecules, 1987, pp. 1300-1311, vol. 20.
Baskir, J. N. et al. “Protein Partitioning Two-Phase Aqueous Polymer Systems”,Biotechnology and Bioengineering, 1989, pp. 541-558, vol. 34.
Bierau, H. et al. “Direct process integration of cell disruption and fluidised bed adsorption in the recovery of labile microbial enzymes”,Bioseparation, 2001, pp. 73-85, vol. 10.
Bleier, J. E. et al. “Assembly and Mixing of Two-Stage Aqueous Two-Phase Protein Extractions”,Biotechnol. Prog., 2001, pp. 697-702, vol. 17.
Bompensieri, S. et al. “Rapid purification of a lipase fromAcinetobacter calcoaceticusby temperature-induced aqueous two-phase systems”,Biotechnology Techniques, Aug. 1998, pp. 611-613, vol. 12, No. 8.
Boschetti, E. et al. “Separation of Antibodies by Liquid Chromatography” InHandbook of Bioseparations, 2000, pp. 536-632, Chapter 15, vol. 2 of the Separation Science and Technology Series, Academic Press, San Diego, California, edited by Satinder Ahuja.
Boschetti, E. et al. “Bioprocess Tutorial: Hydrophobic Charge-Induction Chromatography”,Genetic Engineering, Jul. 2000, pp. 1-4, vol. 20, No. 13.
Cordes, A. et al. “Large-Scale Purification of Formate Dehydrogenase”,Methods in Enzymology, 1994, pp. 600-608, vol. 228.
Costa, M. J. L. et al. “Scale-up of recombinant cutinase recovery by whole broth extraction with PEG-phosphate aqueous two-phase”,Bioseparation, 2000, pp. 231-238, vol. 9.
Devereux, J. et al. “A comprehensive set of sequence analysis programs for the VAX”,Nucleic Acids Research, 1984, pp. 387-395, vol. 12, No. 1.
Diamond, A. D. et al. “Effect of Amino Acid Sequence”,In: Peptide and Protein Partitioning in Aqueous Two-Phase Systems, 1990, American Chemical Society, pp. 52-65.
Dos Reis Coimbra, J. et al. “Continuous separation of whey proteins with aqueous two-phase systems in a Graesser contactor”,Journal of Chromatography A, 1994, pp. 85-94, vol. 668.
Duarte, M. C. T. et al. “Production and purification of alkaline xylanases”,Bioresource Technology, 1999, pp. 49-53, vol. 68.
Eiteman, M. A. et al. “Peptide Hydrophobicity and Partitioning in Poly(ethylene glycol)/Magnesium Sulfate Aqueous Two-Phase Systems”,Biotechnol. Prog., 1990, pp. 479-484, vol. 6.
Eiteman, M. A. et al. “A model for the prediction of partition coefficients in aqueous two-phase systems”,Bioseparation, 1991, pp. 31-41, vol. 2.
Fernandes, S. et al. “Affinity Extraction of Dye- and Metal Ion-Binding Proteins in Polyvinylpyrrolidone-Based Aqueous Two-Phase System”,Protein Expression and Purification, 2002, pp. 460-469, vol. 24.
Grantham, R. “Amino Acid Difference Formula to Help Explain Protein Evolution”,Science, 1973, pp. 862-864, vol. 185.
Guan, Y. et al. “Studies on the Isolation of Penicillin Acylase fromEscherichia coliby Aqueous Two-Phase Partitioning”,Biotechnology and Bioengineering, 1992, pp. 517-524, vol. 40.
Guoqiang, D. et al. “Integration of aqueous two-phase extraction and affinity precipitation for the purification of lactate dehydrogenase”,Journal of Chromatography A, 1994, pp. 145-152, vol. 668.
Hart, R. A. et al. “Large Scale, In Situ Isolation of Periplasmic IGF-I fromE. coli”, Bio/Technology, Nov. 1994, pp. 1113-1117, vol. 12.
Hatti-Kaul, R. “Aqueous Two-Phase Systems”,Molecular Biotechnology, 2001, pp. 269-277, vol. 19.
Haynes, C. A. et al. “Thermodynamic Properties of Aqueous Polymer Solutions: Poly(ethylene glycol)/Dextran”,J. Phys. Chem., 1989, pp. 5612-5617, vol. 93.
Haynes, C. A. et al. “Separation of Protein Mixtures by Extraction: Thermodynamic Properties of Aqueous Two-Phase Polymer Systems Containing Salts and Proteins”, 1989, pp. 463-474, vol. 53.
Johansson, G. et al. “Concentration and purification of β-glucosidase fromAspergillus nigerby using aqueous two-phase partitioning”,Journal of Chromatography B, 1998, pp. 161-172, vol. 711.
Kim, S.-H. et al. “Structural requirements of six naturally occurring isoforms of the IL-18 binding protein to inhibit IL-18”,PNAS, Feb. 1, 2000, pp. 1190-1195, vol. 97, No. 3.
King, R. S. et al. “Molecular Thermodynamics of Aqueous Two-Phase Systems for Bioseparations”,AIChE Journal, Oct. 1988, pp. 1585-1594, vol. 34, No. 10.
Li, Y. et al. “Protein Purification via Aqueous Two-Phase Extraction (ATPE) and Immobilized Metal Affinity Chromatography. Effectiveness of Salt Addition to Enhance Selectivity and Yield of GFPuv”,Biotechnol. Prog., 2002, pp. 1054-1059, vol. 18.
Menge, U. et al. “Purification of Proteins from Cell Culture Supernatants”,Develop. Biol. Standard, 1987, pp. 391-401, vol. 66.
Minami, N. M. et al. “Separation and purification of glucoamylase in aqueous two-phase systems by a two-step extraction”,Journal of Chromatography B, 1998, pp. 309-312, vol. 711.
Novick, D. et al. “Interleukin-18 Binding Protein: A Novel Modulator of the Th1 Cytokine Response”,Immunity, Jan. 1999, pp. 127-136, vol. 10.
Pearson, W. R. “Rapid and Sensitive Sequence Comparison with FASTP and FASTA”,Methods in Enzymology, 1990, pp. 63-98, vol. 183.
Persson, J. et al. “Purification of protein and recycling of polymers in a new aqueous two-phase system using two thermoseparating polymers”,Journal of Chromatography A, 1999, pp. 31-48, vol. 864.
Porath, J. et al. “Metal chelate affinity chromatography, a new approach to protein fractionation”,Nature, Dec. 18, 1975, pp. 598-599, vol. 258.
Porath, J. et al. “Immobilized Metal Ion Affinity Adsorption and Immobilized Metal Ion Affinity Chromatography of Biomaterials. Serum Protein Affinities for Gel-Immobilized Iron and Nickel Ions&

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