Process for the purification of gamma interferon

Details Process for the purification of gamma interferon Process for the purification of gamma interferon

1985-07-03

1988-06-14

Hazel, Blondel

Drug, bio-affecting and body treating compositions

Lymphokine

435 68, 435811, 530351, A61K 4502, C07K 1526, C12P 2100

Patent

active

047510781

ABSTRACT:
A process is disclosed for purifying gamma interferon from various contaminants resulting from disruption of the cell in which the interferon was produced. The process provides for sequential removal of (a) nucleic acids, (b) negatively charged contaminating proteins, (c) positively charged contaminating proteins and (d) low and high molecular weight impurities.

REFERENCES:
patent: 4440675 (1984-04-01), Braude

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