Process for the purification of gabapentin

Details Process for the purification of gabapentin Process for the purification of gabapentin

2008-07-01

2008-07-01

Puttlitz, Karl J (Department: 1621)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acids and salts thereof

Reexamination Certificate

active

10561018

ABSTRACT:
A process for the preparation of gabapentin which comprises the passage of a gabapentin inorganic salt through a strong cationic ionic exchange resin, the elution of gabapentin fixed on the column, the concentration of the resultant solution and the cristallization from organic solvent, characterized in that the elution of gabapentin fixed on the column is carried out by using an ammonia and alkaline hydroxide aqueous solution, is described.

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U.S. Appl. No. 10/582,790, filed Jun. 14, 2006, Glovanetti et al.
U.S. Appl. No. 10/561,018, filed Dec. 16, 2005, Cotarca et al.
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U.S. Appl. No. 11/722,056, filed Jun. 18, 2007, Giovanetti et al.

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