Process for the production of γ-keto acetals

Details Process for the production of γ-keto acetals Process for the production of γ-keto acetals

2007-02-13

2007-02-13

Solola, Taofiq (Department: 1626)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C549S375000

Reexamination Certificate

active

11055645

ABSTRACT:
A process for the production of a γ-ketoacetal compound wherein the desired product is obtained by a simple procedure in a high yield as a high purity product. The reaction scheme for the process is as follows:wherein Ar is an aryl group; X is a halogen atom; Raand Rbis an alkyl or alkoxy group; andW is an alkylene group.

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Khanna I.K.; Weier R.M.; Yu Y.; Collins P.W.; Miyashiro J.M.; Koboldet C.M.; Veenhuizen A.Q.; Currie, J.L.; Seibert K.; Isakson P.C., “1,2-Diarylpyrroles as Potent and Selective Inhibitors of Cyclooxygenase-2”,J. Med. Chem., (1997), vol. 40, pp. 1619 to 1633.
English-language International Preliminary Examination Report dated Feb. 18, 2004 of International application PCT/JP2003/010471 filed Aug. 19, 2003; Applicant: Sankyo Company, Limited.

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