Process for the production of ursodesoxycholic acid

Details Process for the production of ursodesoxycholic acid Process for the production of ursodesoxycholic acid

1982-07-14

1984-01-10

Roberts, Elbert L.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

C07J 900

Patent

active

044252749

ABSTRACT:
An improved process for the preparation of ursodesoxycholic acid or 3.alpha.,7.beta.-dihydroxy-cholanic acid in high yields by reducing 3.alpha.-hydroxy-7-keto-cholanic acid with lithium in liquid ammonia.

REFERENCES:
patent: 4282161 (1981-08-01), Guillemette
Kiek, "Steroid Reaction Mechanisms", (1968) Elsevier Publishing Co., (New York), pp. 131-143.
Anderson et al., "Journal of Biochemistry", (1962), pp. 236-242.
Djerassi et al., "Steroid Reactions", (1963), Holden-Day Inc. pp. 276-277.

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