Food or edible material: processes – compositions – and products – Processes – Separating a starting material into plural different...
Reexamination Certificate
2005-01-04
2005-01-04
Paden, Carolyn (Department: 1761)
Food or edible material: processes, compositions, and products
Processes
Separating a starting material into plural different...
C426S601000, C424S439000, C424S725000, C549S413000, C203S043000, C203S074000, C203S080000, C203S081000
Reexamination Certificate
active
06838104
ABSTRACT:
This invention relates to processes for the production of tocotrienol compounds from biological sources such as palm oil, cereals, grains, and grain oils. The tocotrienol products are recovered in high yields. These tocotrienols are useful as pharmaceuticals, in foodstuffs and as dietary supplements. These compositions are hypocholesterolemic, antioxidizing, antithrombotic, antiatherogenic, antiinflammatory and immunoregulatory in nature. Tocotrienols are known to lower the levels of low density lipoproteins in the bloodstream.
REFERENCES:
patent: 4480108 (1984-10-01), Foster
patent: 4603142 (1986-07-01), Burger et al.
patent: 5190618 (1993-03-01), Top et al.
patent: 5487817 (1996-01-01), Fizet
patent: 5504220 (1996-04-01), Kuo et al.
patent: 5512691 (1996-04-01), Barnicki et al.
patent: 5660692 (1997-08-01), Nesburn et al.
patent: 5670669 (1997-09-01), Hunt
patent: 5786491 (1998-07-01), Hamlin et al.
patent: 5932261 (1999-08-01), Unnithan
patent: 6159347 (2000-12-01), Sumner, Jr. et al.
patent: 6177114 (2001-01-01), Unnithan
patent: 6197357 (2001-03-01), Lawton et al.
patent: 6204290 (2001-03-01), Lane et al.
patent: 6224717 (2001-05-01), Sumner, Jr. et al.
patent: 6350453 (2002-02-01), Tan et al.
patent: 6706898 (2004-03-01), Sumner, Jr.
patent: 20020042527 (2002-04-01), Summer, Jr.
patent: 0 333 472 (1989-09-01), None
patent: 06 193178 (1994-07-01), None
patent: WO 9707113 (1997-02-01), None
patent: WO 9824779 (1998-06-01), None
patent: WO 0043095 (2000-07-01), None
patent: WO 0043095 (2000-09-01), None
patent: WO 0071531 (2000-11-01), None
Diplock, A.T., et al., “Relationship of Tocopherol Structure to Biological Activity, Tissue Uptake, and Prostaglandin Biosynthesis,”Ann. N.Y. Acad. Sci. 570:72-84, The New York Academy of Sciences (1989).
Fukuzawa, K., et al., “Increased Platelet-Activating Factor (PAF) Synthesis in Polymorphonuclear Leukocytes of Vitamin E-Deficient Rats,”Ann. N.Y. Acad. Sci. 570:449-454, The New York Academy of Sciences (1989).
Kritchevsky, D. and Story, J.A., “Fiber, Hypercholesteremia, and Atherosclerosis,”Lipids 13:366-369, American Oil Chemists' Society (1978).
Niki, E., et al., “Inhibition of Oxidation of Biomembranes by Tocopherol,”Ann. N.Y. Acad. Sci. 570:23-31, The New York Academy of Sciences (1989).
Qureshi, A.A., et al., “Dietary tocotrienols reduce concentrations of plasma cholesterol, apolipoprotein B, thromboxane B2, and platelet factor 4 in pigs with inherited hyperlipidemias,”Am. J. Clin. Nutr. 53:1042S-1046S, American Society for Clinical Nutrition (1991).
Qureshi, A.A., et al., “Lowering of serum cholesterol in hypercholesterolemic humans by tocotrienols (palmvitee),”Am. J. Clin. Nutr. 53:1021S-1026S, American Society for Clinical Nutrition (1991).
Qureshi, A.A., et al., “The Structure of an Inhibitor of Cholesterol Biosynthesis Isolated from Barley,”J. Biol. Chem. 261:10544-10550, The American Society of Biological Chemists, Inc. (1986).
Qureshi, A.A., et al., “Suppression of Cholesterogenesis by Plant Constituents: Review of Wisconsin Contributions to NC-167,”Lipids 20:817-824, American Oil Chemists' Society (1985).
Serbinova, E., et al., “Free Radical Recycling and Intramembrane Mobility in the Antioxidant Properties of Alpha-tocopherol and Alpha-tocotrienol,”Free Radic. Biol. Med. 10:263-275, Pergamon Press (1991).
Skinner, W.A. and Parkhurst, R. M., “Antioxidant Properties of α-Tocopherol Derivatives and Relationship of Antioxidant Activity to Biological Activity,”Lipids 5:184-186, American Oil Chemists' Society (1970).
Tan, D.T.S., et al., “Effect of palm-oil-vitamin E concentrate on the serum and lipoprotein lipids in humans,”Am. J. Clin. Nutr. 53:1027S-1030S, American Society for Clinical Nutrition (1991).
Pending Non-Provisional U.S. Appl. No. 10/246,760, Bartok et al., filed Sep. 19, 2002 (Not Published).
Pending Non-Provisional U.S. Appl. No. 10/285,700, Binder et al., filed Nov. 1, 2002 (Not Published).
International Search Report for International Application No. PCT/US 01/48624, mailed Jul. 10, 2002.
Kato, A., et al., “Separation of tocotrienols,”Chemical Abstracts 105:775, Abstract No. 105:172787q, American Chemical Society (1986).
Archer Daniels Midland Company
Kirkpatrick & Lockhart LLP
Paden Carolyn
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