Process for the production of tetrazolyl compounds

Details Process for the production of tetrazolyl compounds Process for the production of tetrazolyl compounds

1996-08-16

1998-06-09

Richter, Johann

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

548252, 548253, 544236, 546112, C07D25706, C07D48702, C07D22104

Patent

active

057636192

ABSTRACT:
Disclosed is a method for removing a protective group of an N-protected tetrazolyl compound which comprises reacting said N-protected tetrazolyl compound with a mineral acid under substantially anhydrous conditions in the presence of an alcohol, insuring a high reaction yield of the object tetrazolyl compound.

REFERENCES:
patent: 5196444 (1993-03-01), Naka et al.
patent: 5371233 (1994-12-01), Daumas et al.
Protoghese, "Discovery of a Novel Class of Orally Active, Non-Peptide Angiotensin II Antagonists", Journal of Medical Chemistry, (1992).

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