Process for the production of tetrazolyl compounds

Details Process for the production of tetrazolyl compounds Process for the production of tetrazolyl compounds

1995-01-27

1996-11-26

Springer, David B.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

548250, C07D25704

Patent

active

055787339

ABSTRACT:
Disclosed is a method for removing a protective group of an N-protected tetrazolyl compound which comprises reacting said N-protected tetrazolyl compound with a mineral acid under substantially anhydrous conditions in the presence of an alcohol, insuring a high reaction yield of the object tetrazolyl compound.

REFERENCES:
patent: 5196444 (1993-03-01), Naka et al.
patent: 5371233 (1994-12-01), Daumas et al.
Discovery of a Novel Class or Orally Active, Non-Peptide Angiotensin II Antagonists, J. Med. Chem. 1992 35:3714-3717.

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