Process for the production of teicoplanin

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Using a micro-organism to make a protein or polypeptide

Reexamination Certificate

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C435S252100

Reexamination Certificate

active

07432080

ABSTRACT:
The present invention provides a newly isolated mutant culture ofActinoplanes teichomyceticusBNG 2315. This culture is capable of producing teicoplanin more than 60 times productivity than those reported before (e.g.,Actinoplanes teichomyceticusnov. sp. ATCC 31121). The present invention also provides a fermentation process for the production of teicoplanin in an aerobic condition using the mutant strainActinoplanes teichomyceticusBNG 2315 in a culture-medium comprising carbon sources, nitrogen sources and mineral salts.

REFERENCES:
patent: 4239751 (1980-12-01), Coronelli et al.
patent: 2002057853 (2002-07-01), None
patent: 373510 (2003-02-01), None
patent: 2004076836 (2004-09-01), None

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