Process for the production of sustained release drug...

Details Process for the production of sustained release drug... Process for the production of sustained release drug...

2006-01-31

2006-01-31

Lucchesi, Nicholas D. (Department: 3763)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

C424S423000, C424S427000

Reexamination Certificate

active

06991808

ABSTRACT:
Disclosed is an improved sustained release drug delivery device and method of producing such device. The device comprises a drug core in an impermeable cup or impermeable coating layer that is adhered to an uncured suture tab and covered with a permeable polymer coating layer that is similar to the makeup of the suture tab. The permeable polymer coating layer that covers the device, covering the impermeable coating layer and at least a portion of the drug core, is cured (after drying) along with the uncured suture tab. The “cocuring” or one step curing process forms a very strong bond between the outer coating layer to the suture tab preventing leaks.

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Controlled Drug Delivery (Part I, Xue Shen Wu, PhD, pp. 32, 33, 44-46, 63, 66 & 67) Technomic Publishing Co., Inc., 1996.

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