Process for the production of .sup.18 F-2-deoxy-2-fluoro-D-gluco

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

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536 184, 536 185, 536124, C07H 100

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046173862

ABSTRACT:
Process for the production of 2-deoxy-2-fluoro-D-glucose and the corresponding .sup.18 F-compound in which methyl 4,6-O-benzylidine-3-O-methyl-2-O-trifluoromethanesulfonyl-.beta.-D-mannopy ranoside is reacted with a triflating reagent, the resulting compound reacted with CsHF.sub.2, RbF or the corresponding .sup.18 F-compounds, and thereafter the alkyl groups removed by hydrolysis.

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Ishido et al., Chemical Abstracts, vol. 95, 1981, No. 220273t.
Levy et al., Chemical Abstracts, vol. 98, 1983, No. 194270e.
Olesher et al., Chemical Abstracts, vol. 98, 1983, No. 198616v.
Levy et al., Chemical Abstracts, vol. 98, 1983, No. 34857y.

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