Process for the production of substituted thiazolin-dioxetan sub

Details Process for the production of substituted thiazolin-dioxetan sub Process for the production of substituted thiazolin-dioxetan sub

1995-05-25

1998-01-27

Gerstl, Robert

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving luciferase

C12Q 166

Patent

active

057121060

ABSTRACT:
Compounds of the general formula III, ##STR1## in which R represents ##STR2## and in which R.sub.1 and R.sub.2 are the same or different and represent hydrogen or straight-chained or branched lower alkyl C.sub.1 -C.sub.6, and X represents a cleavable group, at least one of the groups R.sub.4 or R.sub.5 represents a group that stabilizes the dioxetan structure and at most one of the groups R.sub.4 or R.sub.5 represents hydrogen. These compounds can be used as substrates in immunological assays and in DNA diagnostics using activating agents for the formation of colour.

REFERENCES:
patent: 5068339 (1991-11-01), Schapp

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