Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1983-11-16
1985-06-18
Raymond, Richard L.
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
2605024R, C07F 930, C07F 938, C07F 965
Patent
active
045242119
ABSTRACT:
There are prepared 1-amino-2-mercapto-2-methylpropyl phosphonic acid or 1-amino-2-mercapto-2-methylpropyl alkylphosphinic acids of the formula ##STR1## in which Y is hydroxy or an alkyl group by reacting thiazoline-(3) with a phosphonic acid dialkyl ester or an alkylphosphinic acid alkyl ester and then hydrolytically splitting the thiazolidinyl phosphonic acid dialkyl ester or thiazolidinyl alkylphosphinic acid alkyl ester. The thiazolidinyl compounds are new compounds. The 1-amino-2-mercapto-2-methylpropyl phosphonic acid and the 1-amino-2-mercapto-2-methylpropyl alkylphosphinic acids are needed for pharmaceutical purposes.
REFERENCES:
patent: 4443609 (1984-04-01), Alink et al.
patent: 4469686 (1984-09-01), Andrews
Kudzin, Synthesis No. 8, 1981, pp. 643-645.
Drauz Karlheinz
Koban Hans G.
Martens Jurgen
Schwarze Werner
Degussa - Aktiengesellschaft
Raymond Richard L.
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