Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Ortho-hydroxybenzoic acid or derivative doai
Patent
1985-07-26
1986-12-30
Friedman, Stanley J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Ortho-hydroxybenzoic acid or derivative doai
514419, 514561, A61K 3140, A61K 3161, A61K 31195
Patent
active
046329218
ABSTRACT:
The invention relates to a process for the production of pharmaceutical preparations based on 5-aminosalicylic acid in which the 5-aminosalicylic acid is mixed with physiologically and toxicologically acceptable, basic auxiliaries and/or buffer mixtures, which in a 1% aqueous solution give pH-values in the range from 8 to 12, and the mixture obtained is processed in known manner to form tablets, film tablets, dragees, capsules or suppositories, or in which the 5-aminosalicylic acid is mixed with a concentrated aqueous solution of the above-mentioned basic auxiliaries and/or buffer mixtures, the 5-aminosalicylic acid salt formed is precipitated, separated off from the aqueous solution and dried and the salt obtained is processed in known manner to form tablets, film tablets, dragees, capsules or suppositories.
REFERENCES:
patent: 4243749 (1981-01-01), Sadek et al.
patent: 4312806 (1982-01-01), Lambert
patent: 4440763 (1984-04-01), Lover
patent: 4496553 (1985-01-01), Halskov
Chem. Abst (94)-25034t, (1981).
Chem. Abst (98)-46774G, (1983).
Friedman Stanley J.
Schneider Walter H.
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