Plastic and nonmetallic article shaping or treating: processes – Formation of solid particulate material directly from molten...
Patent
1995-09-20
1999-07-06
Harrison, Robert H.
Plastic and nonmetallic article shaping or treating: processes
Formation of solid particulate material directly from molten...
241 23, 241 29, 264 44, 424484, 424489, 424499, 424500, 424501, C08J 312, C08J 316
Patent
active
059194081
ABSTRACT:
The invention relates to a process for the production of pseudolatices or micro- and/or nanoparticles, in which a polymer is crystalline, partially crystalline or amorphous, is selected from cellulose derivatives, poly(meth)acrylates, shellac, polylactides, polylactide/polyglycolide mixtures, polyhydroxy butyric acids or polycyanoacrylates and is heated to a temperature above its glass transition temperature and then high-pressure homogenized in water or an aqueous buffer solution and this suspension is converted, if necessary, into micro- and/or nanoparticles by drying. Medicaments can be worked into the pseudolatices, micro- and/or nanoparticles.
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Evelyn B. Draper and Charles H. Becker, "Some Wax Formulations of Sulfaethylthiadiazole Produced by Aqueous Dispersion for Prolonged-Release Medication," Journal of Pharmaceutical Sciences, vol. 55, No. 4, Apr. 1966, pp. 376-380.
Junis-Specht Felix
Muller Bernd W.
Harrison Robert H.
Pharmatech GmbH
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