Process for the production of optically active cyanohydrins

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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546330, 548561, 549 75, 549442, 549552, 558351, C07C12000, C07C207327, C07C33316, C07C31754

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active

048597848

ABSTRACT:
Optically active cyanohydrins are produced by the reaction of an aldehyde with hydrocyanic acid in the presence of D-oxynitrilase (E.C.4.1.2.10). The reaction takes place in an organic solvent which is not miscible with water, but which is saturated with water or an aqueous buffer solution.

REFERENCES:
patent: 1984415 (1934-12-01), Macallum
patent: 2101823 (1937-12-01), Dittmar
patent: 3850976 (1974-11-01), Shibuya et al.
patent: 4554102 (1985-11-01), Dong et al.
patent: 4594196 (1986-06-01), Stoutamire et al.
Biochemische Zeitachrift 346, 301-321 (1966), "Uber das Flavinenzym D-Oxynitrilase"-Becker and Pfeil.

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