Process for the production of optically active 2-hydroxy-4-pheny

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing oxygen-containing organic compound

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435280, 435822, 435824, 435830, 435836, 435840, 435843, 435850, 435852, 435853, 435857, 435873, 435874, 435885, 435911, 435921, 435930, C12P 742, C12R 122, C12R 101, C12R 1645

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052886204

ABSTRACT:
Optically active 2-hydroxy-4-phenyl-3-butenoic acid can be obtained by treating 2-oxo-4-phenyl-3-butenoic acid with an optionally treated microorganism capable of asymmetrically reducing the 2-oxo-4-phenyl-3-butenoic acid into (R)-2-hydroxy-4-phenyl-3-butenoic acid or (S)-2-hydroxy-4-phenyl-3-butenoic acid to thereby asymmetrically reduce the same into (R)-2-hydroxy-4-phenyl-3-butenoic acid or (S)-2-hydroxy-4-phenyl-3-butenoic acid.

REFERENCES:
Nerdel et al., (1956), Chem. Ber., 89:671-677.

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