Process for the production of N-substituted morpholine and piper

Organic compounds -- part of the class 532-570 series – Organic compounds – Four or more ring nitrogens in the bicyclo ring system

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546192, 570197, C07D26530, C07D29502, C07D21114

Patent

active

047851007

ABSTRACT:
A process is provided for the production of N-substituted morpholines and piperidines of the formula ##STR1## comprising the steps of (a) reacting a methallylbenzene of the formulas ##STR2## wherein R.sub.1 is H or a straight or branched chained C.sub.1 -C.sub.4 alkyl group, alone or in admixture with a corresponding isobutenylbenzene of the formula ##STR3## wherein R.sub.1 is as defined above, with hydrogen bromide in the presence of a peroxide to yield, respectively, the corresponding bromine compound of the formula ##STR4## wherein R.sub.1 is as defined above, alone or in admixture with a bromine compound of the formula ##STR5## wherein R.sub.1 is as defined above and wherein the bromine atom is in the secondary or tertiary position, and

REFERENCES:
patent: 4241058 (1980-12-01), Pfiffner

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