Process for the production of N-substituted-aminomethylphosphoni

Details Process for the production of N-substituted-aminomethylphosphoni Process for the production of N-substituted-aminomethylphosphoni

1990-07-31

1992-03-24

Lee, Mary C.

Organic compounds -- part of the class 532-570 series

Organic compounds

Phosphorus esters

558166, C07F 938, C07F 940

Patent

active

050990560

ABSTRACT:
A process for the production of N-substituted aminoethylphosphonic acid derivatives represented by the formula (I) is disclosed ##STR1## wherein R.sub.1 is an alkyl having 1-18 carbon atoms or a cycloolkyl having 3-18 carbon atoms and R.sub.2 is hydrogen, methyl or ethyl. This process comprises the steps of: reacting N-alkyl and N-cycloalkylhexahydro-s-triazine of formula ##STR2## with trialkylphosphites of formula

REFERENCES:
patent: 4351779 (1982-09-01), Maier
patent: 4442044 (1984-04-01), Purdam
Ikeda, K. et al., Chem. Pharm. Bull. 29(4), 1156-1159 (1981).

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