Process for the production of modified nucleic acids

Details Process for the production of modified nucleic acids Process for the production of modified nucleic acids

1994-06-06

1998-04-21

Zitomer, Stephanie W.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

435 912, 935 77, 935 78, C12Q 168, C12P 1934

Patent

active

057416370

ABSTRACT:
Process for the production of nucleic acids by hybridization of at least one primer to a template nucleic acid and enzymatic elongation of the primer to a nucleic acid strand which is complementary to the template nucleic acid by reaction with different types of nucleoside triphosphates, wherein the complementary nucleic acid strand carries two or more groups which enable it to be immobilized and one or more detectable groups, a method which uses this process for the detection of nucleic acids, suitable reagent kits therefor and modified nucleic acids.

REFERENCES:
patent: 4358535 (1982-11-01), Falkow et al.
patent: 4581333 (1986-04-01), Kourilsky et al.
patent: 4683195 (1987-07-01), Mullis et al.
patent: 4683202 (1987-07-01), Millis
patent: 4711955 (1987-12-01), Ward et al.
patent: 4851331 (1989-07-01), Vary et al.
patent: 4965188 (1990-10-01), Mullis et al.
Gene Anal. tech. 6, 79 (1989) Jansen et al.
Nucleic Acids Research 16, 8719 (1988) Lo et al.
Anal. Biochem. 178,239 (1989) Mitchell et al.
Nucleic Acids Research 16, 11327 (1988) Syvanen et al.
Nucleic Acids Research 147, 4937 (1989) Hultman et al.
Proc. Natl. Acad. Sci. USA 86, 2423 (1989) Kemp et al.
Nature 340, 733 (1989) Uhlen.
Proc. Natl. Acad. Sci. USA 86, 2757 (1989) We et al.
Nucleic Acids Research Symp. Ser. 20, 91 (1988) Yamane et al.
Anal. Biochem. 177, 90 (1989) Schowalter et al.
Proc. Natl. Acad. Sci, 1986 6230-6234 Saiki et al.
Proc. Natl. Acad. Sci, 1990, 87, 8923-8927 D.A. Nickerson et al.
Heiles et al., Biotechniques 6(10):978-981 (1988).
Lo et al., Nuc. Acids Res. 16(17):8719 (1988).
Misiura et al., Ibid. 18(15):4345-4354 (1990).

Affiliated with

Also associated with

Rating

Process for the production of modified nucleic acids does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for the production of modified nucleic acids, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for the production of modified nucleic acids will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2056599